Altered motor coordination, vocal communication, and cerebellar circuit connectivity in mice carrying a near-complete human chromosome 21

Stander, R, Ayyappan, N, Sikorski, D, Van der Heijden, ME, Hsiao, K (2025) – article in: Translational Psychiatry

Modeling Laryngeal Dystonia through Spectral Analyses of Vocalizations in a Dystonia Mouse Model
Fitzgerald, AL, Coello, JA, Lyon, AM, Dao, BL, Van der Heijden, ME^(2025) – preprint on: bioRxiv

Purkinje Cell spike patterns do not correlate with nuclei cell spike patterns in mouse models for cerebellar disease
Lyon, AM, Van der Heijden, ME^(2025) – preprint on: bioRxiv

Cerebellar nuclei cells produce distinct pathogenic spike signatures in mouse models of ataxia, dystonia, and tremor
Van der Heijden, ME*^, Brown, AM*, Kizek, DJ, Sillitoe, RV.^ (2024) – Article (Version of Record) in: eLife

More Than a Small Brain: The Importance of Studying Neural Function during Development
Dooley, JC, Van der Heijden, ME (2024) – Review in: Journal of Neuroscience

Converging and Diverging Cerebellar Pathways for Motor and Social Behaviors in Mice
Van der Heijden, ME (2024) – Review in: Cerebellum

Glutamatergic cerebellar neurons differentially contribute to the acquisition of motor and social behaviors
Van der Heijden, ME*, Rey Hipolito, AG*, Kim, LH, Kizek, DJ, Perez, RM, Lin, T, Sillitoe, RV. (2023) – Article in: Nature Communications

Propranolol modulates cerebellar circuit activity and reduces tremor
Zhou, J., Van der Heijden, M. E., Salazar Leon, L.E., Lin, T., Miterko, L.N., Kizek, D.J., Perez. R.M., Pavešković, M., Brown, A.M. Sillitoe, R.V. (2022) – Article in: Cells

Influence of data sampling methods on the representation of neural spiking activity in vivo
Van der Heijden, ME,Brown, AM, Sillitoe, RV. (2022) – Article in: iScience

Quantification of Behavioral Deficits in Developing Mice with Dystonia-like Behaviors
Van der Heijden, ME,Gill, JS, Rey Hipolito, AG, Salazar Leon, LE, Sillitoe, RV. (2022) – Article in: Dystonia

Cerebellar dysfunction as a source of dystonic phenotypes in mice
Brown, AM, Van der Heijden, ME, Jinnah, HA, Sillitoe, RV (2022) – Article in: Cerebellum

Causal evidence for cerebellar role in prefrontal-hippocampal interaction in spatial working memory decision-making
Liu, Y, McAfee, SS, Van der Heijden, ME, Dhamala, M, Sillitoe, RV, Heck, DH. (2022) – Article in: Cerebellum

Ankyrin-R links Kv3.3 to the spectrin cytoskeleton and is required for Purkinje neuron survival
Stevens, SR, Van der Heijden, ME, Ogawa, Y, Lin, T, Sillitoe, RV, Rasband, MN. (2022) – Article in: Journal of Neuroscience *Cover image

Maturation of Purkinje cell firing properties relies on neurogenesis of excitatory neurons
Van der Heijden, ME,Lackey, EP, Perez, R, Ișleyen, FS, Brown, AM, Lin, T, Zoghbi, HY, Sillitoe, RV (2021) – Article in: eLife

Neuromodulation of the cerebellum rescues movement in a mouse model of ataxia
Miterko, LN, Lin, T, Zhou, J, Van der Heijden, ME, Beckenhausen, J, White, JJ, Sillitoe, RV (2021) – Article in: Nature Communications

Abnormal cerebellar function and tremor in a mouse model for non-manifesting DYT6
Van der Heijden, ME, Kizek, DJ, Perez, R, Ruff, EK, Ehrlich, ME, Sillitoe, RV (2021) – Article in: Journal of Physiology
*Cover image

Purkinje cell misfiring generates high-amplitude action tremors that are corrected by cerebellar deep brain stimulation
Brown, AM, White, JJ, Van der Heijden, ME,Zhou, J, Lin, T, Sillitoe, RV (2020) – Article in: eLife

Function and dysfunction of the dystonia network: an exploration of the circuits underpinning the acquired and isolated dystonias
Gill, JS, Nguyen, MX, Hull, M, Van der Heijden, ME, Nguyen, K, Thomas, S, Sillitoe, RV (2023) – Review in: Dystonia

Cerebellar dysfunction in rodent models with dystonia, tremor, and ataxia
Van der Heijden, ME*^, Sillitoe, RV^ (2023) – Review in: Dystonia

Physiology of Dystonia: Animal Studies
Rey Hipolito, AG*, Van der Heijden, ME*, Sillitoe, RV (2023) – Book chapter in: International Review of Neurobiology

Silencing the output of cerebellar neurons using cell type-specific genetic deletion of vesicular GABA and glutamate transporters
Van der Heijden, ME, Brown, AM, Sillitoe, RV (2022) – Book chapter in: Neuromethods: Measuring Cerebellar Function

Motor control: Internalizing your place in the world
Van der Heijden, ME, Brown, AM, Sillitoe, RV (2021) –Dispatch in: Current Biology

Abnormal cerebellar development in autism spectrum disorders
Van der Heijden, ME*^, Gill, JS, Sillitoe, RV^ (2021) – Review in: Developmental Neuroscience

Interactions between Purkinje cells and granule cells coordinate the development of functional cerebellar circuits
Van der Heijden, ME, Sillitoe, RV (2021) – Review in: Neuroscience